Upstate New York Commercial Real Estate for Sale

70Results

Explore commercial real estate opportunities across Upstate New York, with a concentration of listings throughout Clinton, Essex, and Franklin counties. The region offers a range of retail, office, industrial, and mixed-use properties suitable for various business and investment goals. Buyers and investors can compare locations, review property features, and evaluate access to major transportation routes and local amenities. Contact CENTURY 21 TheOne for strategic local guidance, and sign up to save searches and receive commercial listing alerts.

Newest
New Listing
6137 Sentinel Road Lake Placid NY 12946

$995,000

Lake Placid, NY

6137 Sentinel Road

  • 1955 Year Built
  • 1 Acre
  • 10,606 SqFt
  • 6 Days on Market
MLS#: 207336
New Listing

$485,000

Tupper Lake, NY

95 Park Street

  • 1901 Year Built
  • 0.16 Acres
  • 4,620 SqFt
  • 7 Days on Market
MLS#: 207333
New Listing

$400,000

Saranac Lake, NY

159 Church Street

  • 1960 Year Built
  • 0.19 Acres
  • 1,900 SqFt
  • 11 Days on Market
MLS#: 207295
New Listing

$149,900

Crown Point, NY

3362 Nys Route 9n

  • 2001 Year Built
  • 0.1 Acres
  • 576 SqFt
  • 14 Days on Market
MLS#: 207260
New Listing

$950,000

Lake Placid, NY

1915 Saranac Avenue

  • 1993 Year Built
  • 0.46 Acres
  • 4,800 SqFt
  • 14 Days on Market
MLS#: 207300
New Listing

$340,000

Lewis, NY

8286 US-9

  • 1953 Year Built
  • 0.8 Acres
  • 2,893 SqFt
  • 18 Days on Market
MLS#: 207223
New Listing

$96,000

Keeseville, NY

1843 US-9

  • 1971 Year Built
  • 0.41 Acres
  • 1,580 SqFt
  • 19 Days on Market
MLS#: 207190
New Listing

$750,000

Saranac Lake, NY

36 Broadway

  • 1923 Year Built
  • 0.11 Acres
  • 7,192 SqFt
  • 19 Days on Market
MLS#: 207218
New Listing

$745,000

Keene, NY

10050 Nys Route 9n

  • 1966 Year Built
  • 9.84 Acres
  • 4,824 SqFt
  • 26 Days on Market
MLS#: 207132
New Listing

$695,000

Saranac Lake, NY

97 Main Street

  • 1930 Year Built
  • 0.11 Acres
  • 8,449 SqFt
  • 28 Days on Market
MLS#: 207122
New Listing

$1,200,000

Saranac Lake, NY

9 River Street

  • 1880 Year Built
  • 0.27 Acres
  • 6,811 SqFt
  • 30 Days on Market
MLS#: 207102

$995,000

Wilmington, NY

5192 NY-86

  • 1923 Year Built
  • 85.4 Acres
  • 4,500 SqFt
  • 33 Days on Market
MLS#: 207062

 Based on information submitted to NY_ACVMLS as of May 31, 2026 11:52 PM EDT . All data is deemed reliable but is not guaranteed accurate by the MLS. All information should be independently reviewed and verified for accuracy. IDX information is provided exclusively for consumers’ personal, noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.