Upstate New York Commercial Real Estate for Sale

81Results

Explore commercial real estate opportunities across Upstate New York, with a concentration of listings throughout Clinton, Essex, and Franklin counties. The region offers a range of retail, office, industrial, and mixed-use properties suitable for various business and investment goals. Buyers and investors can compare locations, review property features, and evaluate access to major transportation routes and local amenities. Contact CENTURY 21 TheOne for strategic local guidance, and sign up to save searches and receive commercial listing alerts.

Newest
New Listing
5159 U.s. Avenue Plattsburgh NY 12901

$160,000

Plattsburgh, NY

5159 U.s. Avenue

  • 1985 Year Built
  • 0.19 Acres
  • 1,827 SqFt
  • 0 Days on Market
MLS#: 207881
New Listing

$2,195,000

Lake Placid, NY

1970 Saranac Avenue

  • 1900 Year Built
  • 3.1 Acres
  • 14,663 SqFt
  • 10 Days on Market
MLS#: 207780
New Listing

$795,000

Keene, NY

10897 NY-73

  • 1899 Year Built
  • 0.44 Acres
  • 2,765 SqFt
  • 13 Days on Market
MLS#: 207765
New Listing

$599,900

Peru, NY

82 Pleasant Street

  • 1880 Year Built
  • 1.5 Acre
  • 1,532 SqFt
  • 14 Days on Market
MLS#: 207759
New Listing

$335,000

Plattsburgh, NY

109/209 W Bay Plaza

  • 1986 Year Built
  • 0.01 Acres
  • 2,459 SqFt
  • 15 Days on Market
MLS#: 207737
New Listing

$989,950

Massena, NY

7 County Road 42

  • 1960 Year Built
  • 4.3 Acres
  • 33,339 SqFt
  • 30 Days on Market
MLS#: 207610

$3,500,000

Plattsburgh, NY

43 Hamilton Street

  • 1978 Year Built
  • 0.89 Acres
  • 17,568 SqFt
  • 32 Days on Market
MLS#: 207603

$398,995

Au Sable Forks, NY

14233 Route 9n

  • 1905 Year Built
  • 1.57 Acre
  • 5,300 SqFt
  • 36 Days on Market
MLS#: 207531

$200,000

Massena, NY

395 Main Street

  • 1925 Year Built
  • 83,231 Acres
  • 3,450 SqFt
  • 36 Days on Market
MLS#: 207535
5970 Sentinel Road Lake Placid NY 12946

$40,000

Lake Placid, NY

5970 Sentinel Road

  • 1975 Year Built
  • 1,000 SqFt
  • 36 Days on Market
MLS#: 207508

$1,100,000

Tupper Lake, NY

1616 NY-30

  • 2007 Year Built
  • 7.22 Acres
  • 15,000 SqFt
  • 37 Days on Market
MLS#: 207529

$139,900

Chazy, NY

22 Macadam Road

  • 1980 Year Built
  • 85.8 Acres
  • 864 SqFt
  • 38 Days on Market
MLS#: 207514

 Based on information submitted to NY_ACVMLS as of July 16, 2026 7:22 PM EDT . All data is deemed reliable but is not guaranteed accurate by the MLS. All information should be independently reviewed and verified for accuracy. IDX information is provided exclusively for consumers’ personal, noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.